You’ll find below a list of our publications. You can also lookup these links on Research Gate, Google Scholar and Pubmed for additional details on our research.

Voici une liste de nos publications. Vous pouvez également suivre ces liens vers Research GateGoogle Scholar et Pubmed pour obtenir des informations supplémentaires sur nos recherches.

28) Silué N & Campbell-Valois FX, icaR and icaT Are Ancient Chromosome Genes Encoding Substrates of the Type III Secretion Apparatus in Shigella flexneri, mSphere, 2022. >PDF

27) Bajunaid W, Haidar-Ahmad N, Kottarampatel AH, Manigat FO, Silué N, Tchagang CF, Tomaro K, Campbell-Valois FX. The T3SS of Shigella: Expression, Structure, Function, and Role in Vacuole Escape. Microorganisms 2020, Dec 5; 8 (12), 1933. >PDF

26) Nigro G, Arena ET, Sachse M, Moya-Nilges M, Marteyn BS, Sansonetti PJ, Campbell-Valois FX. Mapping of Shigella flexneri’s tissue distribution and type III secretion apparatus activity during infection of the large intestine of guinea pigs. Pathog Dis. 2019 Oct 1;77(7). pii: ftz054. >PDF

25) Tinevez JY, Arena ET, Anderson M, Nigro G, Injarabian L, André A, Ferrari M, Campbell-Valois FX, Devin A, Shorte SL, Sansonetti PJ, Marteyn BS.Shigella-mediated oxygen depletion is essential for intestinal mucosa colonization. Nat Microbiol. Nov;4(11):2001-2009.

24) Silué N, Marcantonio E, Campbell-Valois FX. RNA-Seq analysis of the T3SA regulon in Shigella flexnerireveals two new chromosomal genes upregulated in the on-state. Methods. 2019 Mar 21. pii: S1046-2023(18)30336-0. >PDF

23) Losier TT, Akuma M, McKee-Muir OC, LeBlond ND, Suk Y, Alsaadi RM, Guo Z, Reshke R, Sad S, Campbell-Valois FX, Gibbings DJ, Fullerton MD, Russell RC. AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles. Cell Rep. 2019 Feb 19;26(8):2150-2165.

22) Kang E, Crouse A, Chevallier L, Pontier SM, Alzahrani A, Silué N, Campbell-Valois FX, Montagutelli X, Gruenheid S, Malo D. Enterobacteria and host  resistance to infection. Mamm Genome. 2018 May 21. doi: 10.1007/s00335-018-9749-4.

21) Pinaud L, Ferrari ML, Friedman R, Jehmlich N, von Bergen M, Phalipon A, Sansonetti PJ, Campbell-Valois FX. Identification of novel substrates of Shigella T3SA through analysis of its virulence plasmid-encoded secretome. PLoS One. 2017 Oct 26;12(10):e0186920. >PDF

20) Pinaud L, Samassa F, Porat Z, Ferrari ML, Belotserkovsky I, Parsot C,
Sansonetti PJ, Campbell-Valois FX, Phalipon A. Injection of T3SS effectors not resulting in invasion is the main targeting mechanism of Shigella toward human lymphocytes. Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):9954-9959.

19) Campbell-Valois FX, Pontier SM, Implications of Spatiotemporal Regulation of Shigella flexneri Type three Secretion Activity on Effector Functions: think globally, act locally, Frontiers in Cellular Infection and Microbiology, 2016, 9;6:28. >PDF

18) Vonaesch P, Campbell-Valois FX, Dufour, A Sansonetti PJ and Schnupf, P. Shigella flexneri blocks stress granule formation in epithelial cells, Cellular Microbiology 2016 Jul;18(7):982-97.

17) Arena ET, Campbell-Valois FX, Tinevez J-Y, Nigro G, Marteyn B, Nothelfer K, Sansonetti PJ. Bioimage analysis of Shigella infection reveals targeting of colonic crypts, Proc Natl Acad Sci USA. 2015, Jun 23;112(25):E3282-90. doi: 10.1073/pnas.1509091112. >PDF

equal contributions

16) Campbell-Valois FX*, Sachse M, Sansonetti PJ, Parsot C. Escape of Actively Secreting Shigella flexneri from ATG8/LC3-positive vacuoles is facilitated by IcsB and VirA, MBio, 2015, MBio, 2015, May 26; 6(3). pii: e02567-14. >PDF

*Corresponding author

15) Campbell-Valois FX*, Schnupf, P, Sansonetti PJ. Design of a Transcription-based Secretion Activity Reporter (TSAR) for the Type III secretion apparatus of flexneri and uses thereof,, 2014, Oct 20; vol. 4 issue 20.

*Corresponding author

14) Campbell-Valois FX*, Schnupf, P, Sansonetti PJ. Detection of the secreted and cytoplasmic fractions of IpaB, IpaC and IpaD by lysozyme permeabilization,, 2014, Oct 20; vol. 4 issue 20.

*Corresponding author

13) Campbell-Valois FX, Sansonetti PJ, Tracking Bacterial Pathogen infection with genetically-encoded reporters, FEBS Letters, 2014 Aug 1;588(15):2428-36. >PDF

12) Grishin AM, Condos TEC, Barber KR, Campbell-Valois FX, Parsot C, Shaw GS, Cygler M. Structural basis for the inhibition of host protein ubiquitination by Shigella effector kinase OspG, Structure, 2014 Jun 10;22(6):878-88.

11) Campbell-Valois FX*, Schnupf P, Nigro G, Sachse M, Sansonetti P, Parsot C. A fluorescent reporter reveals on/off regulation of the Shigella Type III Secretion Apparatus during entry and cell-to-cell spread, Cell Host & Microbe. 2014 Feb; 15(2): 177-189. >PDF

*Corresponding author

10) Campbell-Valois FX*,†, Trost M*,†, Chemali M, Dill BD, Laplante A, Duclos S, Sadeghi S, Rondeau C, Morrow IC, Bell C, Gagnon E, Hatsuzawa K, Thibault P, Desjardins M*. Quantitative proteomics reveals that only a subset of the endoplasmic reticulum contributes to the phagosome. Mol Cell Proteomics. 2012 Jul; 11(7): M111.016378. >PDF

*Corresponding authors; equal contribution

9) Remy I, Campbell-Valois FX, Michnick SW Detection of protein-protein interactions using a simple survival protein-fragment complementation assay based on the enzyme dihydrofolate reductase. Nat Protoc. 2007; 2(9): 2120-5.

8) Campbell-Valois FX, Michnick SW. Protein engineering on Raf-Ras binding domain reveals a polarized distribution of residues with high f-values, but energetically diffuse transition state. J Mol Biol. 2007; 365(5): 1559-77.

7) Campbell-Valois F-X, Michnick SW. Synthesis of degenerated libraries of the Ras-binding domain of Raf and rapid selection of fast-folding and stable clones with the dihydrofolate reductase protein fragment complementation assay. Methods Mol Biol. 2007; 352: 249-74.

6) Campbell-Valois FX, Tarassov K, Michnick SW. Massive Sequence Perturbation of the Raf- Ras Binding Domain Reveals Relationships between Sequence Conservation, Secondary Structure Propensity, Hydrophobic Core Organization and Stability. J Mol Biol. 2006; 362(1): 151-71.

5) Campbell-Valois FX, Tarassov K, Michnick SW. Massive sequence perturbation of a small protein. Proc Natl Acad Sci USA. 2005; 102(42): 14988-93. >PDF

4) Campbell-Valois FX, Michnick SW. Chemical Biology on PINs and NeeDLes. Curr Opin Chem Biol. 2005; 9(1): 31-7.

3) Michnick SW, Valois FX. Gene function: getting specific, generally speaking. Proc Natl Acad Sci USA. 2002; 99(26): 16513-5.

2) Michnick SW, Remy I, Campbell-Valois FX, Vallée-Bélisle A, Pelletier JN. Detection of protein-protein interactions by protein fragment complementation strategies. Methods Enzymol. 2000; 328:208-30.

1) Pelletier JN, Campbell-Valois FX, Michnick SW. Oligomerization domain-directed reassembly of active dihydrofolate reductase from rationally designed fragments. Proc Natl Acad Sci USA. 1998; 95(21): 12141-6.